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2005
Benzimidazole derivatives
R 0200
Synthesis and Antiviral Activity Against Coxsackie Virus B3 of Some Novel
Derivatives. — A series of novel benzimidazole derivatives (V)
19- 134 Benzimidazole
(18 examples) are synthesized and evaluated for their antiviral properties. All the compounds testet display excellent antiviral activity against Coxsackie virus B3. The most
potent compounds (VIa) and (VIb) are even much more active than the standard drug
ribavirin. — (CHENG, J.; XIE, J.; LUO*, X.; Bioorg. Med. Chem. Lett. 15 (2005) 2,
267-269; Sch. Chem. Chem. Eng., Shanghai Jiaotong Univ., Shanghai 200240, Peop.
Rep. China; Eng.) — R. Staver
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