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2005
Thiopyran derivatives
R 0370
Synthesis of Novel Heteroarotinoids with Receptor Activation Capabilities and
Activity. Single Crystal Analysis of (E)-4-[(2,3-Dihydro-2,2,4,4-tetrameth19- 151 TGase
yl-2H-1-benzo[b]thiopyran-6-yl)-1-propenyl]-2-methylbenzoic Acid. — A pathway for the synthesis of title compounds (III) and (IV) is described and an X-ray diffraction analysis for the acid is given. The activation of RARs by heteroarotinoids is
studied for the first time. — (SUBRAMANIAN, S.; SMITH, C. M.; TABATABAI, A.;
BRYAN, C. D.; BUETTNER, B.; HALE, S.; WAKEFIELD, C. A.; BENBROOK, D.
M.; BERLIN*, K. D.; Phosphorus, Sulfur Silicon Relat. Elem. 180 (2005) 1, 67-77;
Dep. Chem., Okla. State Univ., Stillwater, OK 74078, USA; Eng.) — H. Haber
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