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2005
Oxazole derivatives
R 0220
Synthesis and Hetero-Michael Addition Reactions of 2-Alkynyl Oxazoles and
— The title compounds are synthesized by coupling of amino alcohols
21- 132 Oxazolines.
with alkynoic acids followed by cyclodehydration of the resulting amides in the presence of DAST. Oxazolines are obtained which on treatment with BrCCl3 and DBU
afford the target oxazoles (to be continued). — (WIPF*, P.; GRAHAM, T. H.; Org.
Biomol. Chem. 3 (2005) 1, 31-pp; Dep. Chem., Univ. Pittsburgh, Pittsburgh,
PA 15260, USA; Eng.) — Klein
2005
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