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2005
Fused pyrimidine derivatives
R 0515
First Report on the Abnormal Dearylation/Alkylation Reaction in One-Pot
Synthesis with 6-Amino-1,3-dimethyl Uracil. — One-pot three-compo21- 166 Hantzch
nent condensation of aminouracil (I) with aldehydes (II) and acetylacetone affords the
expected dihydropyrimidines (IV) along with dehydrogenated products (VI) and the
abnormal dearylated/dealkylated product (V) on increasing reaction times. —
(AGARWAL, A.; CHAUHAN*, P. M. S.; Synth. Commun. 34 (2004) 24, 4447-4461;
Med. Process Chem. Div., Cent. Drug Res. Inst., Lucknow 226 001, India; Eng.) —
H. Toeppel
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