close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Furan derivatives
R 0060
Non-Thiol Farnesyltransferase Inhibitors: N-(4-Aminoacylamino-3-benzoylpheAcid Amides and Their Antimalarial
22- 097 nyl)-3-[5-(4-nitrophenyl)-2-furyl]acrylic
Activity. — 8 Title compounds of type (IV) and (V), are prepared and their antimalarial
activities is studied. The compounds show high farnesyltransferase inhibitory activities. Compared to the reference compounds, which carry no amino substituent in the
phenylacetic acid part of the molecule, the in vitro antimalarial activities are detrimentally influenced. — (KETTLER, K.; WIESNER, J.; SILBER, K.; HAEBEL, P.;
ORTMANN, R.; SATTLER, I.; DAHSE, H.-M.; JOMAA, H.; KLEBE, G.;
SCHLITZER*, M.; Eur. J. Med. Chem. 40 (2005) 1, 93-101; Inst. Pharm., Zent.
Pharmaforsch., Ludwig-Maximilians-Univ., D-81377 Muenchen, Germany; Eng.) —
M. Bohle
Документ
Категория
Без категории
Просмотров
0
Размер файла
17 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа