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2005
Pyridazine derivatives
R 0500
Synthesis, Analgetic and Antiinflammatory Activities of the Compounds Obby Recyclization of 3-Imino-3(H)-furanones-2 with Substituted Hydra24- 144 tained
zines. — Recyclization of furanones (I) in the presence of hydrazines provides access
towards dihydropyrazinone derivatives (III) or, in the case of dinitrophenylhydrazine
(IV), towards N-aminopyrrolinones (V). All of the compounds prepared possess no
antiinflammatory activity, but some of them show analgetic activity. —
(ROUBTSOV, A. E.; KOVYLYAEVA, N. V.; ZALESOV, V. V.; Khim.-Farm. Zh. 39
(2005) 1, 13-16; Dep. Chem., Perm State Univ., Perm 614990, Russia; Russ., Abstr.
Eng.) — Mischke
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