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2005
Thiophene derivatives
R 0090
Studies on 2-Aminothiophenes: Synthesis, Transformations, and Biological Evalof Functionally-Substituted Thiophenes and Their Fused Derivatives. —
26- 061 uation
Starting from tetrahydrobenzothiophenes (I), a series of functionally-substituted
thiophenes (VI), (X), (XV) are synthesized and transformed into related fused derivatives (VIII), (XIII), (XVI). Selected samples are evaluated for their antibacterial and
fungicidal activity. Derivatives (VIa) and (XIII) are the compounds showing strongest
antimicrobial effects. — (WARDAKHAN*, W. W.; GABER, H. M.; OUF, S. A.;
SHERIF, S. M.; Phosphorus, Sulfur Silicon Relat. Elem. 180 (2005) 2, 601-618; Natl.
Organ. Drug Control Res., Dokki, Cairo, Egypt; Eng.) — R. Langenstrassen
2005
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