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2005
Hydantoin derivatives
R 0210
Reactions of Cyanothioformamide and Thiohydantoin Derivatives with Some
of Cyanothioacetamide and Other Electrophilic and Nucleophilic
26- 072 Arylidenes
Reagents. — The reactions of thiohydantoins (IV) with arylidenes (V), anthranilic acid
(VII), and anilide (IX) are applied for the synthesis of fused heterocyclic compounds
(VI), (VIII), and (X). The direction of the reaction of cyanothioformamides (I) and
(XVI) with cyanothioacetamides (XIII) depends on the nature of the reagents giving
rise to derivatives (XIV), (XV), and (XVII). All the compounds obtained display a
broad spectrum of antibacterial and antifungal activities. — (EL-SHARIEF*, A. M.
S.; MAHMOUD, F. F.; TAHA, N. M.; AHMED, E. M.; Phosphorus, Sulfur Silicon
Relat. Elem. 180 (2005) 2, 573-589; Dep. Chem., Fac. Sci., Al-Azhar Univ., Cairo,
Egypt; Eng.) — R. Staver
2005
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