close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Receptor binding activity
X 0280
Structure—Activity Relationship Studies on ortho-Substituted Cinnamic Acids, a
New Class of Selective EP3 Antagonists. — A series of ortho-substituted cinnamic
26- 170 acids
of type (I) or (II) is prepared and their binding activity and selectivity on the four
prostaglandin E2 receptors is evaluated. Compounds (I) are very potent and selective
EP3 antagonists. (II) is a very good EP2 agonist and shows promising anti-inflammatory
and analgesic properties. — (BELLEY*, M.; et al.; Bioorg. Med. Chem. Lett. 15
(2005) 3, 527-530; Merck Frosst Cent. Ther. Res., Pointe-Claire-Dorval,
Que. H9R 4P8, Can.; Eng.) — M. Bohle
Документ
Категория
Без категории
Просмотров
0
Размер файла
12 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа