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2005
Fused pyridine derivatives
R 0450
Solvent-Free Microwave Synthesis of Bis-pyrazolo[3,4-b:4',3'-e]pyridines and
of Their Antifungal Properties. — The microwave-assisted synthesis of sev27- 148 Study
enteen bis(pyrazolopyridines) like (III) avoids the use of solvent and extended reaction
times, being a valuable method for the synthesis of the title compounds from aldehydes
especially, from which the targets are formed only in low yields by using conventional
methods. The new tricyclic azoles (III) display moderate antifungal in vitro activity
against dermatophytes. — (QUIROGA, J.; PORTILLA, J.; INSUASTY, B.; ABONIA,
R.; NOGUERAS*, M.; SORTINO, M.; ZACCHINO, S.; J. Heterocycl. Chem. 42
(2005) 1, 61-66; Dep. Quim. Inorg., Univ. Jaen, E-23071 Jaen, Spain; Eng.) —
H. Hoennerscheid
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