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2005
Alkaloids
U 0600
27- 196
Novel Inhibitors of Acetyl- and butyrylcholinesterase Derived from the Alkaloids
Dehydroevodiamine and Rutaecarpine. — A variety of fused quinazolines related to
the title alkaloids are prepared and evaluated as possible inhibitors of acetylcholinesterase and butyrylcholinesterase. Most of the tested quinazolines show moderate to
potent acetylcholinesterase inhibitory activity. — (DECKER, M.; Eur. J. Med. Chem.
40 (2005) 3, 305-313; Fachbereich Pharm. Chem., Friedrich-Schiller-Univ., D-07743
Jena, Germany; Eng.) — R. Staver
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