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2005
Furan derivatives
Furan derivatives
R 0060
Mucohalic Acid in Lewis Acid Catalyzed Mukaiyama Aldol Reaction: A Concise
Method for Highly Functionalized γ-Substituted γ-Butenolides. — A simple, effi28- 116 cient
and selective method for the preparation of a variety of highly functionalized
γ-substituted γ-butenolides is presented. In particular, butenolide (V), a core structure
of some important natural products, is obtained as a single stereoisomer. —
(ANGELL, P.; ZHANG*, J.; BELMONT, D.; CURRAN, T.; DAVIDSON, J. G.;
Tetrahedron Lett. 46 (2005) 12, 2029-2032; Chem. Res. Dev., Pfizer Global Res. Dev.,
Ann Arbor, MI 48105, USA; Eng.) — D. Singer
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