close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Azetidine derivatives
R 0045
Ruthenium-Catalyzed Stereoselective Intramolecular Carbenoid C—H Insertion
β- and γ-Lactam Formations by Decomposition of α-Diazoacetamides. — The
31- 114 for
title reaction affords the corresponding β-lactams in high cis-stereoselectivity and nearly quantitative yields. The reaction is carried out in toluene at 70 °C, but other solvents
such as chloroform, CH2Cl2, acetone, EtOAc or THF lead to similar results. The need
of slow addition technique is unnecessary as well as the use of inert atmosphere. Carbenoid insertion into aromatic C-H bonds is demonstrated in the reaction of (XIII).
Comparing the reactions of (VII) and (X) demonstrates the reactivity preference tertiary C-H > primary C-H. An asymmetric version is also presented. — (CHOI, M.
K.-W.; YU*, W.-Y.; CHE, C.-M.; Org. Lett. 7 (2005) 6, 1081-1084; Dep. Chem.,
Univ. Hong Kong, Kowloon, Hong Kong, Peop. Rep. China; Eng.) — R. Steudel
2005
Документ
Категория
Без категории
Просмотров
0
Размер файла
39 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа