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2005
Fused pyrrole derivatives
R 0160
Synthesis of Fused Indoles by Sequential Palladium-Catalyzed Heck Reaction
N-Heteroannulation. — Two consecutive intramolecular cyclization reactions
32- 125 and
of alkenyl 2-bromo-3-nitrobenzyl ethers give access to a variety of indoles fused at the
3,4-position with six-, seven-, or eight-membered rings. The sequence can be also performed with analogous amides and a malonic acid derivative. — (SOEDERBERG*,
B. C. G.; HUBBARD, J. W.; RECTOR, S. R.; O'NEIL, S. N.; Tetrahedron 61 (2005)
15, 3637-3649; Dep. Chem., W. Va. Univ., Morgantown, WV 26506, USA; Eng.) —
Klein
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