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2005
Fused pyridine derivatives
R 0450
The Preparation and Evaluation of 1-Substituted 1,2,3,4-Tetrahydro- and 3,4-Dihydro-β-carboline Derivatives as Potential Antitumor Agents. — A series of title
32- 147 compounds
(III) and (IV) (13 compounds each) are prepared and tested as antitumor
agents. There is an apparent lack of correlation regarding cytotoxicity between compounds (III) and (IV). (IVd) is chosen as a potential lead for the development of future
anticancer agents. — (SHEN*, Y.-C.; CHEN, C.-Y.; HSIEH, P.-W.; DUH, C.-Y.; LIN,
Y.-M.; KO, C.-L.; Chem. Pharm. Bull. 53 (2005) 1, 32-36; Inst. Mar. Resour., Natl.
Sun Yat-Sen Univ., Kaohsiung, Taiwan; Eng.) — M. Bohle
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