close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Imidazole derivatives
R 0190
Synthesis of 3,9,9,9a-Tetramethyl-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indolby Reaction of 2,3,3-Trimethyl-3H-indole with 2-Bromopropionamides.
35- 135 -2-ones
— The alkylation of indolones (I) with bromopropionamides (II) followed by treatment
with an aqueous alkali base gives rise to the title compounds (III) in moderate yields.
Compounds (III) suffer imidazolidine-ring opening on treatment with HClO4 to afford
3H-indolium perchlorates (IV), which react with 2-hydroxynaphthaldehyde to yield a
diastereomeric mixture of spiro compounds (VI). — (VALAITYTE, E.;
MARTYNAITIS, V.; SACKUS, A.; Chem. Heterocycl. Compd. (N. Y.) 40 (2004) 11,
1460-1464; Dep. Org. Chem., Kaunas Univ. Technol., Kaunas 3028, Lithuania; Eng.)
— R. Staver
Документ
Категория
Без категории
Просмотров
0
Размер файла
22 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа