close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Pyridine derivatives
R 0380
Alkylation of 3-Cyano-4-methoxymethyl-6-methyl-2(1H)-pyridone by Active
Compounds. The Molecular Structure of 3-Amino-2-benzoyl35- 163 Halomethylene
-4-methoxymethyl-6-methylfuro[2,3-b]pyridine. — The direction of the alkylation
reaction of cyanopyridone (I) depends on the nature of the alkylating agent and leads
either selectively to the N-alkylated derivatives (III) or to mixtures of N- and O-alkylated derivatives (IV). The alkylation of compound (I) with bromides (IIa,b) in the
presence of excess amounts of KOH leads to furo[2,3-b]pyridines (V) due to the
Thorpe—Ziegler isomerization of the O-alkylated derivatives. — (KAIGORODOVA,
E. A.; VASILIN, V. K.; SIDOROVA, E. A.; ZAVODNIK, V. E.; KRAPIVIN, G. D.;
Chem. Heterocycl. Compd. (N. Y.) 40 (2004) 11, 1442-1453; Kuban State Technol.
Univ., Krasnodar 350072, Russia; Eng.) — R. Staver
Документ
Категория
Без категории
Просмотров
0
Размер файла
22 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа