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2005
Carboxylic amides
Q 0490
Synthesis and Study of Some New N-Substituted Imide Derivatives as Potential
Agents. — A wide range of N-substituted imide derivatives are synthe36- 071 Anticancer
sized by treating phthalic or naphthalic anhydrides with hydrazine or amine derivatives,
and evaluated for their antineoplastic activity. None of the selected samples exhibit significant cytotoxity. The new aminoglutethimide derivatives (X) shows weak inhibition
of human placental aromatase as compared with aminoglutethimide. — (JINDAL, D.
P.; BEDI, V.; JIT, B.; KARKRA, N.; GULERIA, S.; BANSAL*, R.; PALUSCZAK, A.;
HARTMANN, R. W.; Farmaco 60 (2005) 4, 283-290; Univ. Inst. Pharm. Sci., Panjab
Univ., Chandigarh 160 014, India; Eng.) — A. Forchert
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