close

Вход

Забыли?

вход по аккаунту

?

код для вставки
2005
Multicomponent reactions
O 0359
Three-Component Coupling Reactions of Silylglyoxylates, Alkynes, and AldeA Chemoselective One-Step Glycolate Aldol Construction. — A variety of
37- 056 hydes:
terminal alkynes and aldehydes is successfully employed in the title reaction to give
highly functionalized protected 1,2-diols in good yields and moderate diastereoselectivities. Using (+)-N-methylephedrine/Zn(OTf)2, silyl-deprotected adduct (XI) is
formed with moderate diastereo- and enantioselectivity. Application of the concept to
aliphatic aldehydes results in formation of glycol (XIV) with high diastereoselectivity.
— (NICEWICZ, D. A.; JOHNSON*, J. S.; J. Am. Chem. Soc. 127 (2005) 17,
6170-6171; Dep. Chem., Univ. N. C., Chapel Hill, NC 27599, USA; Eng.) —
S. Adam
2005
Документ
Категория
Без категории
Просмотров
0
Размер файла
36 Кб
Теги
1/--страниц
Пожаловаться на содержимое документа