Патент USA US2131516код для вставки
sept- 27, ‘1938. H. LEFFER'IA ET A1. ‘ 2,131,516 PHARMACEUTICAL APPARATUS Filed Jan. 51, 1956 ~ 1N VENTOR5 HERMAN LEFFE'RT "M $72442 ATTORNEYS Patented Sept. 27, 1938 2,131,516 UNITED STATES igPATENT't OFFICE A 2,131,516 PHARMACEUTICAL APPARATUS Herman Le?’ert and Edward E. Cleve land, Ohio, assignors, by mesneWoldman, assignments, to harmaceutical Company, Inc., New N. Y., a corporation of New York Application January 31, ‘1936, Serial No. '10 Claims. This invention relates to a York, 61,783 ‘ (Cl. 128-—_225) a flask without mixing with any liquid that is utilized for producing the suctio . . _ ’ , Referring now to the vdrawing, Fig. 1 shows one form of apparatus for carrying out our in trating the operation of the apparatus shown in Fig. 2 for withdrawing gas from the stomach of a food into the patient. We have found that patient. ' '10 15' “15 bed and above the level of the rate of ?ow. An object of our invention, In such illustration, the vide an apparatus, which will ing short of the bottom thereof. An intermediate, or air ?ask I4 is disposed be side the medicine ?ask and is connected thereto by a tube l5. The ends of the tube I5 terminate level of the material in a reservoir; A device which has been used for rectal feeding which enters through a tube 2|, a valve 22 being used for 20 from a reservoir controlling the rate of ?ow. At the start medicine is placed in 40 thereof. Consequently there is no danger of dis charging an excessive quantity into the patient at any time. i A further advantage of our apparatus is the fact that it ’ 50 material to be mixed with water or other liquid that is used to create the suction. ‘In our appa ratus, the extracted material can be collected in It. By adjusting the valve 22 any desired number of drops per minute will enter 56 2,131,516 2 the ?ask l4, and the corresponding volume of liquid will be dispensed from the ?ask l3. If de sired, the discharge tube may be temporarily dis connected from the stomach tube during the syphoning action, so as to prevent the ?ow of an excess quantity of medicine into the patient, but as soon as the medicine ?ows at the same rate at which water enters the ?ask I4, the discharge tube is connected to the stomach tube. Such dis amount to drop from the container 31 into the compartment 34. In this way, there is a con stant head in the compartment 35 as a result of which the adjustment of the valve 45 maintains a uniform low rate at all times. As soon as the material in the ?ask 30 is dis a larger quantity of liquid than the ?ask 30 so -" that there is ample liquid in reserve to assure a discharge of the entire contents of the ?ask. There is a slight difference in the operation of the apparatus illustrated in Fig. 1 from that il - 5 lustrated in Fig. 2 in that no syphoning action in the apparatus of Fig. 2 occurs at the time the I will not be objectionable. As soon as the level of medicine in the ?ask l3 drops below the entrance in the discharge tube, 15 then the valve 22 is closed, the reservoir 2| and the ?ask l3 are re?lled and the ?ask I4 is emptied. Ordinarily, the ?ask l3 holds a su?icient quan 20 a period of twenty-four hours. (11 charged, the ?ask may be re?lled, the compart ment 33 drained, and the container 31 re?lled. In practice, the container 31 is arranged to hold connection is not necessary in all cases, for it medicine used is not harmful, the delivery of an excess quantity for a very short period of time tity of medicine for permitting medication for _ dispensing operation is initiated. Furthermore, there are less connections in which air leaks may ti’: ’ occur. - To minimize the number of connections and thereby to avoid the possibility of air leakage into the vacuum line, and at the same time to vWhile we have explained our invention in con nection with stomach medication, it is apparent that the apparatus may be used for rectal feed ing, in which case the stomach tube is replaced by a rectal tube. The apparatus is likewise well eliminate the necessity of utilizing a ?uid under adapted for use as a suction pump to remove gas' pressure to start the ?ow of material into the and liquid material from the stomach in post 25 dispensing tube, we have shown a modi?cation of operative treatment. To use the apparatus for’ our invention which is illustrated in Fig. 2. In the latter purpose, it is only necessary to connect such modi?cation, the material to be dispensed it as shown in Fig. 3 and to have the ?ask 30 is placed in a container 30 which has a discharge ~empty and the compartment 33 ?lled with water. ' 30 tube 3| leading from the bottom thereof. ' The valve 46 is closed, the valve 32 is fully opened, A valve 23 in the discharge tube prevents the and then the valve 4| is adjusted so as to allow ?ow of material therefrom until the apparatus liquid to drain from the compartment 33 at the is in condition for operation. The ?ask 30 has desired rate. As the level of liquid in the com a stopper 25 into which a tube 32 extends. The partment 33 drops, gas or liquid contents are ?ask end of the tube terminates above the level drawn into the ?ask 30 to replace the liquid which of the material-in the ?ask while the opposite end is drained from the compartment 33. of the tube is in communication with an air tight While we have shown in each modi?cation an chamber 33. The chamber or compartment 33 apparatus wherein a partial vacuum is utilized for may be formed within a container 34 which has restraining the rate of ?ow, and have illustrated 40 another compartment 35 in which water or other apparatus by means of which the volume of air in liquid can be held. A gas and liquid tight parti the reservoir space above the liquid is auto tion 36 separates the two compartments. The container 34 is illustrated as supporting a con tainer 31 which is likewise adapted to hold water, and which is provided with a discharge opening 45 38 in the bottom thereof. A ?oat controlled valve 40 is carried by the container 31, and is adapted to control the ?ow of water through the open ing 38 from the tank 31 into the tank 34, the adjustment being such that the level in the tank 34 is maintained at the same position at all times. .; At the start of the operation, the compart ment 33 is empty, and the valve 4| in the drain 55 conduit 42 is closed. Accordingly,‘ as soon as the stomach tube is connected‘ to the discharge tube 3|, the valve 23 is opened, and the material in the ?ask 30 starts to ?ow and to rarify the air in the compartment 33.‘ As soon as the air is rari?ed to the point where it will support the head of material in the ?ask, the ?ow ceases, and thereafter, it is allowed to continue only in accordance with the rate at which air in the compartment 33 is displaced. Such displace 65 ment occurs by allowing water to flow from the compartment 35 into the compartment 33 through a by-pass 45 that is controlled by a valve 46. A portion of the by-pass comprises a glass tube by means of which the number of drops per minute can be observed. The rate of ?ow from 70 the compartment 35 to the compartment 33 is therefore, the identical rate at which material is allowed to flow from the ?ask 30.‘ As soon as liquid ?ows from the compartment 15 35, the ?oat controlled valve 40 allows the same matically varied so as to assure a continuous ?ow at a uniform rate, nevertheless we may, if desired, eliminate the water reservoir, as well as 4 the intermediate compartment into which the water is allowed to drip, and vent the vacuum space by means of the valve 46. The valve may be adjusted so as to bleed into the vacuum space a very small quantity of air which acts as a vent to allow the liquid to flow out of the container. The valve may be opened to any desired degree so as to regulate the rate of ?ow. An important advantage of our invention is the fact that material may be introduced into a 5 5 patient automatically at a constant predeter mined rate. This is valuable in the treatment of stomach ulcers, as it permits medication without interfering with the normal introduction of food through the oral cavity. The apparatus is quite 60 simple in arrangement and compact in size and is capable of being readily cleaned and sterilized for repeated use. ‘ We claim: 1. In combination, a container for storing ma 65 terial in liquid form, a discharge conduit lead ing therefrom, a vacuum chamber in communi cation with the container above the level of liquid therein, means for introducing a liquid into the chamber to displace the space occupied by a quantity of air therein, and a valve for control ling the rate of ?ow into the chamber whereby liquid from the container will be proportionately released. 2. In combination, a container for liquid, 9. 7. 2,181,516. discharge time leading therefrom, a valve for Cl 3 controlling the flow through the discharge tube, whereby the material is caused to ?ow drop-by a vacuum chamber, a tube connecting the vacu um chamber to the space above the liquid in the the flow of liquid. container, a liquid reservoir, a conduit connecting the reservoir to the vacuum chamber so that liquid may ?ow from the reservoir into the chamber to displace the space occupied by the air therein, and a valve for controlling the rate 10 of flow in the last named conduit whereby liquid from the container will be proportionately re leased. 3. In appar-atus of the character described, comprising in combination, a container for liquid drop in substantially volumetric equality with . 7. An apparatus for dispensing material, com prising a container for material, a discharge con duit leading therefrom, means for maintaining a ?ow of material therefrom, a second container in communication with the space in the first 10 container and means for modifying the volume of air under said vacuum by admitting a liquid into the second container, drop by drop, whereby material, a discharge conduit leading therefrom, the discharge of material from the ?rst container a vacuum chamber in communication with the 15 into the second container. 8. An apparatus for dispensing liquid material, - space above liquid in the container, a reservoir, the chamber being adapted to receive a liquid from the reservoir to displace the space occu pied by the air therein said chamber having a capacity greater than the material in the con tainer, and means for controlling the rate of ?ow‘of liquid into the chamber whereby liquid is substantially identical to the ?ow of liquid drop by drop, for medication or feeding pur poses, comprising in combination, a container for storing‘ the material, a discharge conduit leading therefrom, means for maintaining an air-tight seal within the container so as nor from the container will be proportionately re-‘ ‘‘ mally to prevent the ?ow of material therefrom, an air-tight compartment in communication 25 leased. 4. An apparatus of the character described, with the container and means for ?owing liquid 25 drop by drop into the compartment, whereby comprising in combination, a container for ma the discharge of material from the ?rst contain terial that is to be dispensed, a discharge con er is substantially identical to the flow of liquid duit leading from the container near the bot 30 tom thereof, a receptacle, a reservoir positioned into the second container. 9. An apparatus of the character described, thereabove and adapted to hold liquid, the res ervoir having an opening through which liquid comprising in combination a container for liquid may ?ow into the receptacle, a ?oat controlled material, a- discharge conduit extending down valve for regulating the ?ow from the reservoir wardly into the container and having the en into the receptacle so as to maintain a uniform trance thereto below the level of liquid therein level of liquid at all times in the receptacle, an and having the discharge end thereof positioned 35 air chamber at a lower level than the receptacle, below the entrance end,'a second container in there being a passageway for liquid to flow from communication with the ?rst container above the level of the liquid therein, and means for the receptacle to the chamber, a valve for con 40 trolling the last named ?ow, and means for maintaining a partial vacuum in thespace above the material in the ?rst container so as normally providing communication between the air cham ber and the space in the container above the to prevent the flow of material therefrom, and liquid. 5. In a device of the character described, the 45 combination of a container for holding liquid, a discharge conduit leading from the container so that liquid may ?ow by gravity therefrom, means for controlling the rate of flow, said means comprising a member having a lower air com 50 partment, an intermediate liquid compartment, and a surmounting reservoir, there being a passageway between the reservoir and the inter mediate compartment, and another passageway from the intermediate compartment to the air 55 compartment, means for adjusting the rate of flow from the intermediate compartment to the air compartment and means for maintaining a uniform head of liquid in the intermediate com partment. 60 5 partial vacuum in the space above the material in the container, so as normally to prevent the 6. A method of dispensing material, drop by drop, for medicationor feeding purposes, com prising utilizing above the material a partial vacuum, which normally prevents the flow of material, modifying the volume of air under said 65 vacuum, by utilizing a drop-by-drop flow of liquid other than the material in said partial vacuum, means for ?owing liquid drop by drop into the second container whereby the discharge of ma terial from the ?rst container is substantially identical to the ?ow of liquid into the second 45 - container. 10. A device of the character described, com prising in combination, two containers, each hav ing a stopper, one of the containers having liquid therein and having a conduit extending through the stopper for conveying material therefrom, 50 the entrance to the conduit being below the level of the liquid therein, and the other container having a conduit extending through the stopper for introducing liquid thereinto, there being a third conduit having its ends projecting through 55 the respective stopper , means for maintaining a partial vacuum within the two containers so as normally to prevent the flow of liquid from one of the containers and means for admitting a liquid into the other container drop by drop 60 whereby the discharge of liquid from the ?rst container is substantially identical to the ?ow of liquid into the other container. HERMAN LEFFERT. EDWARD E. WOLDMAN.