Патент USA US2409718код для вставки
Lxamme e95 I Patented Oct. 22, 1946 2,409,718 UNITED STATES PATENT OFFICE 2,409,718 COIMPOSITION FOR CLEANING DENTURES Foster Dee Snell, New York, and Kurt W. Haese ler, Forest Hills, N. Y., assignors to Foster D. Snell, Inc., a corporation of New York No Drawing. Application November 13, 1941, Serial No. 419,028 2 Claims. (01. 252-106) 1 This invention relates to a’ composition for cleaning dentures. - 2 3’,5',6' hexachlorodiphenylmethane in the form of one of its water soluble salts, a water soluble i‘ ‘In the cleaning of false teeth, supporting struc surface tension lowering agent, and a scale dis tures therefor, bridges, or like dentures, there integrating material. Preferably the composition are strict requirements to be met. It is necessary, comprises an oxidizing agent that assists in de for example, that the cleaning composition should stroying certain materials including bacteria and penetrate the scale (plaque) of calcareous de colored, staining materials. posits, mucin, and other material accumulated on In addition to the materials recited the com the dentures and disintegrate such scale to read position may contain odor or taste establishing ily removable form, remove the loosened scale, de 10 materials and a relatively large proportion of stroy the odor of any stale saliva present, and inert diluent such as salt. disinfect the dentures, all without the necessity The invention is illustrated by the composition of abrasives or brushing. It is also necessary that shown in the following table, proportions here the cleaning material in small proportions be and elsewhere herein being expressed as parts by non-toxic to humans but effective as a germicide. 16 weight. Also, it should be either practically tasteless and Denture cleaning composition odorless or of pleasant taste and odor. For satis factory distribution and use, it should be avail able in substantially non-caking, powder “form, and dissolve with reasonable ease w?erf'added’to" 20 Proportion ingredient water. The resulting aqueous solution must not alter the established color of the plate. These requirements are more severe than for Range Sodium salt of 2,2’ dihydroxy 8,5,?-3’,5’.6’ hexachloro-diphenylmethane (disinfectant) compositions to be used in cleaning natural teeth. ‘ Sodium rborate (oxidizing agent)_.._..___.._ Conventional compositions for natural teeth are 25 Tetraso ium pyrophosphate (scale disinte grating material) .................... ._‘__.. preformed pastes, liquid solutions of surface-ac Sodium lauryl sulfa-acetate (surface ten ion tive agents, powders containing abrasive, etc. for application on a moist brush. Compositions for the two purposes are not satisfactorily inter changeable. In cleaning natural teeth, the teeth 30 Preferred lowering agent) ........... U‘. _ . . . _ _ _ _ _ _. Tricalcium phosphate (anticaking agen ___Oil of peppermint (to establish odor) . _ _ _ __ Sodium chloride (diluent) _________________ _. 0. 5—2 0.7 6-10 10 20-70- 50 ' -l.~5—5 - 2—3 2 3 0. 5-1 0. 5 To maliretlllw parts 0 a are invariably moist and brushing is employed. Arti?cial dentures are frequently dry and the The ingredients are mixed dry in any suitable deposits to be removed are more ?rmly placed due manner, commonly with the tricalcium phosphate to such drying. The dentures are constructed of added last for greater effectiveness. Before being porcelain, rubber, plastic, or other materials 35 used, the mixture is dissolved in water, to give an that are entirely different from the calcium phos aqueous solution containing about 2 parts of the phate of the teeth and the live tissue of the gums. mixture to 100 parts of water or other concentra The present invention provides _a_dry,_non-cak tion desired. ingjgpwdefthjatishuickly soluble in water, that To clean used dentures that are of average con meets the requirements set forth for a denture 40 dition Or slightly worse, it is necessary only to im cleaner, and that will clean dentures during im merse the dentures in the aqueous solution for mersion for a quarter of an hour or so, without ?ve to ten minutes. Warm water is usually used. the use of any abrasive or brushing. The compo In particularly obstinate cases the dentures are sition penetrates material caked or dried on the soaked overnight. During this immersion, the dentures, transforms it, loosens it, and then re 45 dissolved composition penetrates the ?lm of cal moves it from the dentures, and causes thorough careous deposit and mucin on the dentures and disinfection. The composition is without bleach ing effect on any part of the dentures, such as loosens not only that, but also other dirt parti cles. In addition, the composition destroys germs pink base plates, and does not cause deposition of at such a rate and so effectively as to meet the salts from hard water used in dissolving the den 50 Federal Food and Drug Administration speci?ca ture cleaning composition previous to use. tions for an “antiseptic.” The composition of the invention which shows While particularly satisfactory results have these properties comprises a disinfectant that is been obtained with the composition described, al- ' unique and for which we know of no alternative ternative materials may be substituted for the in our formula, namely, 2,2’ dihydroxy 3,5,6 various ingredients in the above table. i 2,409,718 3 4 For the disinfectant any of the water soluble salts of 2,2’ dihydroxy 3,5,6-3',5',6' hexachlorodi phenylmethane may be used, as for example, its sodium, potassium, or calcium salt. No other disinfectant has been found satisfactory. lauryl sulfoacetate shown in the table, another In place of the sodium perborate as the oxi~ dizing agent, there may be used other alkali alkali metal higher alkyl sulfate. or a sulfonic acid derivative of a higher alcohol. Thus, there may be used the sulfonic acid derivatives of alco hols containing 12 to 20 carbon atoms to the molecule, the said compounds before incorpora~ tion into our composition being suitably neutral ized by alkali to the stage of being approximately neutral or slightly alkaline. Of the salts of the metal perborates or water-soluble non-poison ous perborates of other metals. Thus, there may be used the perborates of potassium or ammo 10 higher sulfates, there may be used, for instance, nium, either alone or mixed with sodium perbo sodium dodecyl sulfate, sodium hexadecyl sulfate, rate. .Almmonium perborate, however, is some (Ti/sodium octadecyl sulfate, the higher alkyls what too hygroscopic for most satisfactory gen present in these compositions being either eral use. Considering properties and price, so straight or branched chain and saturated or un dium perborate is the most advantageous per 15 saturated, in accordance with commercial prac borate for the present purpose. The perborate tice in the industry of non-soap detergents. has a bleaching effect upon ?lms on the dentures. Another detergent that may be used is the one The proportion of the selected perborate may known as sodium keryl benzene sulfonate. be varied within rather wide limits. Proportions The proportions of the non-soap detergents substantially in excess of ten per cent tend to in 20 used are suitably the smallest amounts that will troduce complications, due to caking of the com give approximately the minimum surface tension positions on long standing, without giving corre of water solutions when the cleaning composition sponding and fully offsetting advantages. Under is dissolved to give the aqueous solution of con some circumstances, however, it is found desir centration suitable for use. Thus, there may be able to exceed the 10% speci?ed. Amounts of 25 used about 1.5 to 5 parts of the non-soap deter sodium perborate less than 5 parts to 100 parts of gent to 100 of dry weight of the whole composi the finished composition are not entirely satis tion. factory from the standpoint of the cleaning The tri'calcium phosphate in the composition power of the whole composition. tabulated above is representative of anti-caking The tetrasodium pyrophosphate used as the 30 agents. It minimizes the tendency of the com scale disintegrating agent may be replaced by position to form itself into a compact mass, dur other molecularly dehydrated complex phos ing storage before use. In place of the calcium phates such as sodium hexametaphosphate, some phosphate for this purpose, there may be used times known as Calgon or in a modi?ed form as powdered corn-starch, precipitated calcium car Calgonite, or by the compound known commer bonate, precipitated magnesium carbonate, or cially as sodium tetraphosphate. In a different other material that is adapted to form a ?ne class as to satisfactoriness, but usable for some coating on particles that, on coming into contact purposes are trisodium phosphate, sodium sesqui with each other, would cake together. The tri carbonate, or similar alkaline salts. Mixtures of calcium phosphate is preferred and gives out the several salts may be used. Also, the metal 40 standing results for this purpose. combined in the salt selected may be either the The oil of peppermint establishes the ?avor sodium described or potassium, ammonium, or and odor. In place of the oil of peppermint or the like. The salt used must be soluble in water, with it, there may be used methyl salicylate, pine stable, and free from objectionable effect upon oil derivatives, or other high boiling esters or the other ingredients of the cleaning composi essential oils of pleasing taste and odor. tion. The proportion of the ?avoring material should It is considered that the complex phosphates be below that amount which, if used, would irri such as tetraphosphate, hexametaphosphate, and tate the tissues of the mouth when the ?avoring the like disintegrate the scale chie?y by seques material is accidentally placed in the mouth in 4.ering_the_alkalinge_art‘h__rnetals such as calcium 50 small proportion. On the other hand, the pro and magnesium present inwt’lié'deposits‘ on'sthe portion of the ?avoring material should not be denture. Trisodium phosphate, sodium sesqui so low as to lose its ?avoring effect, in case such silicate, and the like are considered to function effect is desired in the composition. largely by forming a precipitate of phosphate, The sodium chloride in the formula of the table silicate, and the like with such alkaline earth 55 serves largely as diluent. This salt may be re metals, thus liberating the organic radicals pre placed by other Water-soluble materials that are viously combined with the alkaline earth metals, non-toxic to human beings and without injurious these radicals combining with the alkali metal effect upon the tissues of the body, the dentures, originally present in the phosphate or carbonate, or upon other ingredients of the cleansing com to form alkali metal salts. Such complete chem 60 position. Thus, there may be used in place of ical reformation disintegrates the scale or plaque the sodium chloride such salts as sodium sulfate so that it is readily removed, the complex phos or potassium chloride. phates serving this purpose especially effectively. In making the substitutions of the various al The proportion of the phosphate or the alter ternative materials for those given in the table native therefor is suitably in the range of about 65 above, the substitution should be made on the 20 to 70 parts for 100 parts of the ?nished com basis of equal proportions. Thus, 1 part of the position. Proportions larger than 70 parts lead material shown in the table is replaced by ap to waste due to extra expense without compensat proximately 1 part of the alternative material. ing advantages, whereas amounts much less than In a typical test, there was used the composition 20 parts give imperfect cleansing of the dentures. 70 shown in the table above containing 0.7 part of As the non~soap detergent or surface-tension the antiseptic to 100 parts dry weight of the com lowering agent, there is used a water-soluble or position and such a dilution with water as to give ganic compound containing both lipophylic and a solution containing 2.5 parts of the said com hydrophylic groups, these groups being present in position to 100 parts of water. This solution test the same molecule, as, for example, the sodium 76 ed for germicidal properties under standard con LU“ LIL/lltl LAGHHHUZ 5 2,409,718 ditlons shows no growth after 5, 10, or 15 min utes. Under comparable conditions, phenol di luted with 80 times its weight of water permitted growth after 5 minutes’ treatment but no growth after either 10 or 15 minutes. It will be understood that the details given are for the purpose of illustration, not restric tion, and that variations within the spirit of the invention are intended to be included in the scope of the appended claims. What we claim is: 6 chloride as diluent to make 100 parts total, all proportions being by weight. 2. A denture cleaning composition comprising a dry free ?owing powder of the following compo sition: sodium salt of 2,2’ dihydroxy, 3,5,6-3’,5',6' hexacmorodiphenylmethane 0.5-2 parts as dis infectant, a water-soluble, non-toxic perborate 5-10 parts, an alkali metal molecularly dehy drated phosphate 20-70 parts, a powdered anti 10 caking agent 2-3 parts, a surface tension lower ing agent selected from the group consisting of 1. A denture cleaning composition comprising a higher alkyl sulfates and sulfonates 1.5-5 parts, dry free ?owing powder of the following compo and a non-toxic water soluble salt serving as a sition: sodium salt of 2,2’ dihydroxy 3,5,6~3',5',6' diluent in proportion to make 100 parts of the hexachlorodiphenylmethane 0.5-2 parts, sodium 15 whole composition, all proportions being by perborate 5-10 parts, tetrasodium pyrophosphate weight. 20-70 parts, sodium lauryl sulfo-acetate 1.5-5 FOSTER DEE SNELL. parts, tricalclum phosphate 2-3 parts, and sodium KURT W. HAESELER.