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Nov. '5, 1946.
M. R. FIELDS
2,410,43s
SIFTER PAckAGB Eon‘ PHARMACEUTICALS
‘ Fiiéd Jan. '5, 1944
s Sheets-Sheet 1
m
'gy'. (I
' Nov. 5,x 1946. .
M. R._ FIELDS-
‘
_
' 2310,43
. SIFTER’PACKAGE FOR PHARMACEUTICALS
Filed Jan. 6, 1944
r
.
'S'SheetS-Sheet 2
-
- Nov- 5, 1946»
M. R. 'F'ms-
2,410,438
SIFTER PACKAGE FOR PHARmAcBbTicALs
Filed Jan.‘ 6, 1944 '
:s Shegts-Shee’c s
Patented Nov. 5, 1946 ~
2,410,438
. UNITED
STATES
PATENT OFHCE‘
2,410,438
SIFTER PACKAGE FOR PHARMACEUTICALS
Mack R. Fields, Chicago, Ill., assignor to Abbott
Laboratories, a corp oration of Illinois
Application January 6, 1 944, Serial No. 517,212
6 Claims. . (Cl. 206-6322)
1
2
This invention relates to the packaging of pow
dered or similar pharmaceutical preparations in
Fig. 15-is aperspective illustrating the method '
of opening the sitter end of the inner package
for dispensing purposes. ‘
a manner in which the preparation may be main
tained in a sterile condition and conveniently
Referring now to the drawings, the outer en
velope consists of a suitabl e paper blank having a
-main wall-formin g panel l5. From the opposite
sides of the panel Hi, there extend ?aps i6 and I‘!
which are adapte d to be folded inwardly over
‘ the
i5 toform the second or other side wall
of the outer envelope. ‘The ?ap It has its margin
dispensed by sifting directly from the package.
The package herein described is designed par
ticularly for the packaging of certain sulfa drugs
in granular form which are employed in surgery
by being sprinkled or sifted into the incision or
into open wounds for control of infection.
_
The main objects of the invention are to pro
vide a package of the character indicated, the
component parts of which may be manufactured
by more -or less conventional envelope-making
coated with adhesive, as indicated at it, and such
adhesive engages the outside surface of the flap
ll, as will be apparent from an inspection of Fig.
2, to permanently unite said ?aps and to hold
bers at a high rate of speed; to provide such a 15 them in their co-operating wall-forming position.
The upper end portions of the flaps l6 and I‘!
package which may be easily opened by the per
have corner portions cut away, or recessed, and
son about to use it immediately before sifting ma
terial from the package into the incision or
wound; to provide such a package which will be
effective to maintain its contents sterile notwith; 20 ened longitudinally,
standing the
indicated at'Zl and 22.
As shown, the slits I 9asand
20 terminate short of
the lines 23 and 2!
y and’quickly filled and as
ll are folded relative
sembled; and , in general, it is the object-of the
panel l6 and, in the '
invention to provide an improved package of the 25 folded condition of the _ ?aps, the tear lines 21
and
22
extend
upwar
character indicated.
dly and slightly inwardly
from the inner ends of said slits.
Other objects and advantages of the improved
pack
'
From the upper end
machineryand thereby produced in large num
30
In the drawings,
Fig. 1 is a plan of a bl
ank
from which an outer 35 an angle that they
v
shown at 33. When
Figs. 2 and 3 illustrate succ
steps in fold
ing the blank of Fig. 1 to form essive
Fig. 4 is a plan showing the outer envelope ,'
envelope is formed; -
the 'outer envelope 40
completely formed, an inne r envelope
being also
outer envelope;
' Fig. 5 is a plan
of a blank from which there is
formed an inner envelope;
‘
Fig. 6 is a
'
Fig. 5
Fig. 7 is a perspective
inner envelope in its closed condition; _
Fig. 8 is a plan of the upper or sifter end of
the inner envelope in the partially folded condi
tion illustrated in Fig. 6;
.
Figs. 9, 10 and 11 are side elevations, Fig. 10
being partially in section, illustrating successive
steps in the closing of the sifter end of the inner
envelope;
'
Figs. 12, 13 and 14 are perspectives illustrating
he opening of the package
preparatory to dispensing the contents oi’ the in
ner envelope, and
‘
preparation (or other mate
The inner envelope is preferably of the con
struction shown in Figs. 5 to 11 inclusive. It
60 is formed from a blank having the form illus
carcass
-
.trated in Fig. 5 and which comprises a main
panel 36, side flaps 31 and 38 extending from
the side edges of said main panel, and top and
bottom ?aps 38 and 48 respectively extending
from the top and bottom ends of the said main
any cause of adhesion to the walls of the outer
envelope.
‘
-
-
The inner envelope may be filled with the de
.
sired quantity of sulfanilamide, or other phar
maoeutical preparation or material, through the
remaining open bottom end of the envelope
panel 3‘. The ?ap 31 is provided with a stripe
'4! of adhesive extending longitudinally thereof
whereupon the open bottom end may be closed
by folding the lower end flap 48 over the open
adjacent but spaced inwardly from the free side 10- end to the position illustrated in Fig. 7. The ‘
edge thereof, and it is folded inwardly over the
flap 4! may be adhesively secured in its closed
main panel 36 and over the side ?ap 38 which
position as indicated.
.
inwardly
over
the
panel
36.
'
is initially folded
The inner envelope with its content of material
The ?aps 31 and 38 are thus adhesively united , may then be inserted through the open bottom
to form the second side wall or the inner en
of the outer envelope illustrated in Fig. 3. Dur
velope, the main panel 38 forming the ?rst wall.
ing the handling of the inner envelope, suitable
15
The upper end ?ap 39 embodies an outer end
precaution is, of course, exercised to maintain
portion 42 and inner portions 43 and 44. The
the sifter end in its ?attened closed position, as
portion 42 'is connected to the portion 43 by a
illustrated in Figs. 7 and ll, so that the content
suitable fold line 45, and the portions 48 and
of the envelope will not be discharged through
44 are similarly connected to each other by a
fold‘line 46, the portion 44 being connected to
20
the end of the panel 38. by a fold line 41. The
sections 43 and 44 havetheir ends notched, as
indicated at 48 and 48 respectively and they are
provided with a plurality of suitably spaced
diamond-shaped openings ‘58*, which have their
major dimension extending transversely of the
intermediate fold line 46, and their minor di
mension parallel to and in alignment with said
‘the Sifter end. After the inner envelope is in
serted into the outer envelope, a ?ap 52 which
projects from the lower end of the main panel
I! of the outer envelope, is folded into closed po
sition overlying the outer envelope wall formed
by the flaps l6 and II. The said bottom ?ap 52
may be provided with a. suitable coating of adhe
‘sive, as indicated at 53, which will adhesively se
cure the flap 52 to the wail-forming ?aps l8 and
I1 so as to maintain the outer envelope closed.
fold line 46.
The‘ package formed as above described may
After the side ?aps 31 and 38 are folded into
be made of a suitable grade of paper, preferably
the wall-forming position illustrated in Fig. 6,
a strong, ?ne-grain paper which is not excessively
the top end ?ap 38 is folded through the steps
porous. The entire package is then preferably
illustrated in Figs. 6 to 11 inclusive to form a
subjected to a sterilizing treatment which may
sifter end closure and to close the upper end
or the envelope. The upper end ?ap sections 43 35 consist of a dry heat'treatment for a period of
about two hours at a temperature of around
and 44 are folded into face-to-face engagement
285° F.
'
or to a position approaching such face-to-face
Tests have indicated that when the package
engagement, as clearly shown in Figs. 6 and 9;
is formed as above described, and sterilized in
then- the side edges of the partially formed en
the manner indicated, it will remain sterile in
V40
velope are pressed toward-each other so as to
de?nitely at least so far as the interior of the
cause the side walls thereof to bulge and sep
outer envelope and the inner envelope are con
arate as shown in Figs. 6 and 8. When the
cerned. Some care should; of course, be exer
envelope is thus caused to open, it will be ob
cised to make sure that the adhesive stripe 28
served that the inwardly notched ends 48 and
which seals the upper end ?ap of the outer en
48 of the flap sections 43 and 44 cause the ends
velope to the body thereof forms an imperforate
of the folded sections to lie within the open end
line of junction between the ?ap 25 and the wall
of the envelope,‘ and the V-shaped notches‘ in 4 formed by the flaps I8 and i1, and alsothat suf
each section 43 and 44 serve to facilitate curving
flcient, adhesive is applied to the lower ?ap 52
- of the folded ?ap portions ,43 and 44 into con
50 to hold the said ?ap in tight face-to-face en
formity with the-curvature of the wall 36.
gagement with the underlying wall of the en
The next step in the folding oi the sitter end
velope. ‘ It is perhaps not essential that adhesive
of the envelope is to fold the flap portion 42
be employed between all of the area of‘ the ?ap
downwardly over the upper end of the wall formed ' 52 and the underlying surfaces of- the envelope,
by the ?aps 31 and 38, thereby incidentally tum
but“ it is desirable that care be exercised to in
ing the folded sections 48 and 44 downwardly 55 sure tight folding of the ?ap over the end of the
into the open end of the envelope, as shown in '
Fig. 10. Upon completion of the‘ downward fold
ing of the flap section '42, the upper end of
the envelope may again be ?attened or closed, 60
the sections 43 and 44 being then brought into
face to face engagement with each other and
with the respective walls of'the envelope so that
the said sifter end is e?ectively closed. The flap.
section 42 may be adhesively’secured in closed
.
envelope so that there remains no distended
opening between’ the ?ap and the underlying wall‘ '
of the envelope. The same consideration is ap
plicable in respect of the sealing of the upper
flap 2! to the underlying wallet the envelope.
The preferred method of opening the envelope
so as to maintain sterility of the inner envelope,
or at least, so as to avoid contamination of the
dispensing end portion of the inner envelope, is
illustrated in Figs. l2, l3 and l4.< As there
' shown, the body of the package may be grasped
in one hand while an unsecuredmai‘ginal end
' tion 42.
portion of the top ?ap 28 is gripped between the
. The adhesive employed in the construction of
the inner envelope is applied in spaced relation 70 ?ngers of the other hand preparatory to pulling
saidiiap upwardly and away from the envelope
to the’ edges of the various flaps so that when
wall to which it is adhesively attached. Sepa
the naps are' folded to their closed positions,
ration of the adhesive joint formed by the adhe
adhesive will not be squeezed out beyond the
sive
stripe 28 is ‘facilitated by_ reason of the an
edges of the ?aps. the ‘outside .of the envelope
being thereby maintained clean and free from 76 gular disposition of the portions 8| and 32 of the
position by the provision of a suitable stripe ii
of adhesive on the inside surface of the flap sec
8,410,438
5
.
said adhesive stripe which results in a point 33
in which the- tearing force is initially localized
and from which the separation proceeds grad
ually toward each side. Such progressive sepa
ration is much easier to accomplish than would
be the simultaneous separation of the entire
length of an equivalent transverse line’of adhe
sive. In the course of unfolding the ?ap 25, the
adhesive connections between the ?ap and the
When the inner envelope is inserted into the
outer envelope, it is desirable that'some care be
exercised to center it therein so that when the
package is opened, the inner envelope will be
substantially midway between the tear lines 2|
and 22. thereby to avoid overlapping of the inner
envelope by the side wall areas 53 and 55 of the
outer envelope. The length of the inner en~
velope is preferably such as to ?t snugly within
portions 34 and 35 of the side walls are not sep 10 the length of the outer envelope; this close-?tting
arated but, instead, said portions 84 and 8B are
relation, together with the pinching or gripping
separated from the wall of the envelope. This
effect of the walls of the outer envelope on the.
result is assured by proper regulation of the
inner envelope serves to eilfectively hold the inner
amount and character of the adhesive employed
envelope against sidewise shifting in the outerv
in theareas 26 and 21, and by the provision of 15
the slits l9 and 20 and weakened tear lines 2|
The described structure is capable of some
.and 22. For manufacturing convenience, slight
modi?cation without departing from the prin
bonds may be retained in the slit lines l9 and 20 ' ciples of the structure and such modifications are
near the inner edges of the ?ap portions 3t and
accordingly intended to be covered by some of
35, although such bonds are not essential. Such 20 the appended claims.
'
bonds may be provided as indicated at 53-53 in
I claim:
,
'
,
Fig. 1. The bonds-should be su?iciently narrow
1‘. Apackage of the class described comprising
that they will not interfere with the separation
an inner container, an outer envelope enclosing
of the portions 34 and 35 from the envelope wall
said inner container, said envelope having a pair
along the full length of the slit lines is and 2B.
of walls and a closure flap extending from the ‘
The unfolding movement of the ?ap 25 is con
upper vend. of one of said walls, said ?ap being
tinued rearwardly until the ?ap may be tucked
folded over the outside of the other wall to close
between the ?ngers of the hand holding the body
the envelope‘, said other wall being provided with
of the envelope, as shown in Fig. 14, such folding
va centrally disposed opening in its upper end and
of the ?ap being also accompanied by supple 30 with weakened lines of severance extending out
mentary folding of the body of the outer envelope
wardly- from the side edges de?ning said central,
transversely along a line extending approximately
opening, into proximity to the outer edges of the
at the level of the outer ends 5t—5li of the upper
envelope, and thence upwardly toward the upper
edges of the envelope‘wall formed by the removal
end of the wall, said lines of severance de?ning
of the portions 3t and 35. The angular disposie
readily removable inner corner portions, said ?ap
tion of the tear lines 2| and 22 facilitate such
being adhesively secured to said removable cor
folding by maintaining to a minimum the width
ner portions and also to the wall of the envelope
of the side wall areas 55-55 (Fig. 13) atthe ,
container.
line of fold. Said angular disposition of the tear
'
..
. below said corner portions, said envelope being
adapted to be opened by pulling said?ap from
lines. 2| and 22 serves also to provide adequate 40 said otherwall so as to break the adhesive bond
width of wall with which the side portions of the
between the ?ap and said wall below said remov
adhesive stripe 28 may be engaged, while also
able corner portions, the adhesive bond between
holding down said width sumciently to avoid sub
stantial (if any) overlap of these portions on the.
inner envelope.
.
said flap and said removable portions being of
such strength that said removable portions will
remain united to the ?ap and be removed from
By the opening procedure described, the inner
the envelope wall to thereby ‘form in said envelope
envelope is caused to project substantially from
an opening a?ording free access to said inner
the outer envelope, the sifter end of the inner ene
container.
'
velope being thus exposed. A surgeon about to
2. A package of the class described comprising
employ the contents of the inner envelope, in the 50 an inner container, ‘an outer envelope enclosing
exercise of due caution, may then withdraw the
said inner container, said envelope having a pair
inner envelope‘ by means of a pair of forceps, or
of walls and a closure ?ap extending from the
the like, and proceed to sift the contents oflthe
upper end of one of said walls, said ?ap being
' envelope into an incision or wound.
However, ’
the use of forceps is not a necessity, inasmuch as
a surgeon may grasp the inner envelope at a point
folded over the outside of the other wall to close
,the envelope, said other wall being provided with
a centrally disposed opening in its upper end and
spaced substantiallyfrom the sifter end and with
with weakened lines of severance extending out
draw it from the outer envelope. Then, by press
wardly from the side edges de?ning said central
ing together the edges of the inner envelope near ' opening, into proximity to the outer edges of the '
its sifter end, the walls thereof may be caused to 60 envelope, and thence upwardly and inwardly to- ‘
bulge and the sifter end distended, as shown in
ward the upper end of the wall, said lines of sev
V Fig. 15,-to thereby open the diamond-shaped dis- '
erance de?ning readily removable inner corner
pensing openings, whereupon the contents of the
portions, said flap being adhesively secured to
envelope may be dispensed as required.
removable corner portions, and also .to the
It will be apparent that the described envelope 65 said
wall
of
the envelope below said corner portions and
structure may conveniently be employed by mem
between the latter and the side edges of the en
bers of the armed forces under battle conditions.
velope, said envelope being adapted to be opened
In the case of wounds received under such condi
by pulling said flap so as to break said last-men
tions, the wounded person, ifnot wholly incapaci
tioned
adhesive bond, the adhesive bond between
tated, may easily open the described package 70 said ?ap
and said removable portions being ofv
structure and sift the contents of the inner en
such strength that said removable portions will
velope into his wounds before su?icient time for
remain united to the flap and be removed from
serious infection has elapsed.‘ Accordingly, many
the envelope wall, the upper portion of the wall
otherwise serious infections may be prevented in
from which said ?ap extends being outwardly
their inception.
'
'
~
>
75 ioldable upon itself along a line approximately
:registering with the lower edge of said
2,410.4”
contained
central
the envelope to project therefrom
in readily accessible‘position.
opening in said other wall,:thereby to expose an
end portion of said innercontainer.
'
.
-
6. A package or the class described comprising
‘an inner container and an outer envelope enclos
i
' 3. A package or the class described comprising
an inner, material-containing envelope, an outer 5 ing said inner container, said envelope having a I
Pair of walls and a closure ?ap extending from
envelope having closed ends and an internal
length only slightly greater than the external
the end of one of said walls and folded over the
length of said inner envelope, whereby the closed - ’
adjacent end portion of the other wall to close
the envelope, said other wall being provided with
ends or said outer envelope are eilective to hold
the walls thereof in tight frictional engagement 10 weakened lines of severance cooperating with the
adjacent and edge of the wall to de?ne removable
the ends of the package, thereby to resist shifting . wall material, said lines of severance embodying
of the inner envelope in the outer envelope, one‘. side portions adjacent but spaced inwardly from
the side edges of the wall and extending down
or said closed ends of the outer envelope com
- prising a ?ap extending from-the upper end of 15 wardly from said end edge and lower portions of
one of the walls of the envelope, said ?ap being ‘ said lines of severance extending inwardly from
said marginal side portions, said ?ap being ad
folded over the outside of the other wall to close
with the walls of the innerenvelope adjacent ‘
the envelope, said other wall being provided with - hesively secured in closed position to said remov- ,
a centrally disposed opening in its upper end . able wall material and also to said marginal side
and with weakened lines of severance extending 20 portions, the adhesive bond for said marginal side ‘
portions being weak enough to be breakable by
pulling said ?ap away fromsaid other wall, and
the adhesive bond between said ?ap and said re
movable material being strong enough to cause
the upper end of the wall, said lines of severance ,
de?ning readily removable inner corner portions, ‘as said. material to follow the ?ap and be separated
said ?ap being adhesively. secured to said-re
from the wall when said ?ap is pulled therefrom,
the upper end, portion of the ?ap-bearing wall
movable corner portions and also to~ the wall of
4 the envelope below said corner portions and be
- being bendable away from said inner container
after separation 01’ said removable material from
- tween the latter and the side edges‘ or the en
velope, said outer envelope being adapted to be 30 said other-wall, whereby a portion of said inner
opened by pulling said ?ap from said other wall _
container may be caused to project from said
outer envelope and thereby made readily accessi
so as to break said last mentioned adhesive bond,
"ble for withdrawal from said outer envelope.
the adhesive bond between said flap and said
6. A package of the class described comprising
' removable portions being oi such strength that
said removable portions will remain united to‘ 35 an inner container and an outer envelope enclos
the ?ap and be removed from the outer envelope
ing said inner container, said envelope having a
wall to'thereby enlarge said centrally disposed
pair of walls and a closure ?ap extending from
opening so as to exposed substantially the entire
the end 01 one of said walls and folded over the
width oLthe upper end portion or said inner
adjacent end portion 01 the other wall to close the
envelope, said-inner envelope being so disposed 40 envelope, said other wall being provided, with
outwardly from the side edges de?ning said cen
tral opening, into proximity to the outer edges
of the envelope, and thence upwardly toward
in the outer envelope as to be substantially cen
weakened lines of severance cooperatinglwlth the
trally located relative to said enlarged opening,
thereby facilitating folding of the upper portion
‘of the ?ap-carrying wall away from the exposed
portion of the inner envelope, to thereby a?ord
adjacent and edge of the wall to de?ne removable
wall material, said lines of severance embodying
side portions adjacent but spaced inwardly from
the side edges of the wall and extending down
a
45
free access to the latter.
wardly from said end edge so as to provide nar
4. An envelope having a pair of walls and a
closure ?ap extending from the upper end of
one of said walls, said ?ap being folded over the
outside of the other wall to close the envelope, 50
said other viral! being provided with a centrally
disposed opening in its upper end, and with
weakened lines of severance extending outwardly
from the side edges de?ning said central open
row marginal side portions of the wall outwardly
of said side portions of said lines of severance,
there being also lower portions of_ said lines of
severance extending inwardly from said marginal
side portions, said ?ap being adhesively secured
in closed position to said removable wall material
ing, and into proximity to the outer edges of said
envelope, there being additional lines of severance
extending upwardly from the outer ends of said
and also to said marginal side portions and to
said otherwall below said removable material, the '
adhesive bond to said side portions and below said
removable material being weak enough to be
. breakable by pulling said ?ap away from said
?rst mentioned lines of. severance co-operating
‘other wall, and the adhesive bond between said
with the latter to de?ne readily removable inner
‘flap and said removable material being strong
corner portions oi.’ said other wall, said ?ap being 60 enough to cause said material to follow the ?ap
adhesively secured to said removable corner porand be separated from the wall when said ?ap is
tions and also to said other wall of the envelope
pulled thereirom, the upper end portion of the
?ap-bearing wail being bendable away from said
adjacent but outwardly of said lines of severance,
said envelope being openable by pulling said ?ap
inner container after separation ‘or said remov~
, so as to break said last-mentioned adhesive
bond, the adhesive bond between said ?ap and
able material from said other wall, and said nar
row marginal side. portionsv of the wall being
readily displaceable by said inner container as
an incident to such bending of said ?ap-bearing
said corner portions will remain united to the
?ap, and be removed from the envelope wall, ~ wall, whereby a portion ‘of said inner container
the upper portion oi’ the wall from which said 70 may be caused to project from said outer en
?ap ‘extends being outwardly ioldable upon itself
velope and thereby made readily accessible for
along a line‘approximately registering with the
withdrawal from said outer envelope. ,
lower edge or said central opening when the en
MACK R. FIELDS.
. velope is opened, thereby to permit an element
- said corner portions being of such strength that
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